Venting, Air and Gas Filtration

 

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Pall filters for pharmaceutical air and gas service are optimized for use in prefiltration of compressed or pressurized gases, and sterile air or gas filtration to completely remove particles, droplets, microorganisms like molds, yeasts or bacteria and even viruses and phages. These filters also find wide use in negative pressure applications such as sterile filtration of vacuum break lines on lyophilizers and autoclaves, and sterile and non-sterile venting of tanks and containers. Pall filters for air and gas service are available in a range of proprietary -manufactured hydrophobic filter media, including PTFE and PVDF as well as glass fiber, polypropylene, cellulose and porous stainless steel. Pall air and gas filters can be sized to meet a wide range of flow and pressure drop requirements, from sterile venting in the laboratory to small process flows in pilot operations, from compressed air flows in process scale operations to full scale air supply in large scale aerobic fermentations at ambient or elevated temperatures.

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Venting, Air & Gas Applications

어플리케이션Why filtration is importantHow Pall Can Help
Sterile Venting of: Tanks, Vessels and Transport Containers, Autoclaves, Lyophilizers, Incubators, and Isolators 의약품 공정 중 충전 및 탈수 공정에서는 공기가 관의 안팎으로 이동하게 됩니다. In most cases no airborne particles or microorganisms are allowed to enter critical product or water tanks. Pall Emflon® PFR filters are hydrophobic sterile filters removing microorganisms, viruses and particles. They are integrity testable and validated, also for long-term use. For small scale applications that require SIP capability in a disposable capsule, the Novasip filter can be used. GMP compliant Pall Advanta® housings support high air flow rates for economic system design.
Sterile Filtration of Pressurized Air or Gas: Biotechnical Air Supply, Exhaust Air Filtration, Filling and Blow Fill Seal Operations, and Transport of Liquids Many pharmaceutical and biotechnological processes need pressurized air or gas as a basic requirement for optimized operation or cell growth. In most products and processes no particles or microorganisms are allowed to enter via air or gas supply lines whereas biohazardous organisms are not allowed to leave into the environment.
Sterile Filtration of High Flow Fermentor Air Supply 최대 100m3 또는 그 이상의 대형 발효기를 작동할 때는 멸균 공기의 유량이 매우 높아야 세포가 효과적으로 성장할 수 있습니다. Historically, large glass fiber towers or multiple narrow bore cartridges have been used. Wide bore Emflon® sterile filters provide flow rates of up to 5000 Nm3/h/cartridge (3000 SCFM/cartridge). 시스템 규모가 작고 자본 비용이 적게 들며 사용하기 쉬운 것이 핵심 장점입니다. 해당 필터는 완전성을 테스트할 수 있으며, 충전탑 및 기존 다중 카트리지 멸균 공기 필터에 대한 경제적이고 안전하며 효율적인 대안으로 검증받았습니다. 오래 사용하면서 압력이 적게 떨어지도록 하려면 사전 필터를 함께 사용할 수도 있습니다.
Venting and Sterile Filtration of Pressurized Air or Gas in Extreme Environments Some processes in the biopharmaceutical industry that needs sterile air filtration or venting operations are running at higher temperatures. 극한의 환경 조건에서 표준 소재를 사용할 수 없는 경우 공정 안전에 영향이 미칠 수 있습니다. Special air filter elements like Emflon® CFR filters with improved material resistance are able to provide safety and long service lives in environments with higher temperatures or elevated oxidation stress.

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